1992
Foundation of Clinical Investigations Ltd, London, UK – International Clinical Trials Projects
1994
Foundation of Clinical Investigations Kft, Budapest, Hungary – Medical Headquarters for Trials in Central Europe
2002
Foundation of Appletree AG, by Dr. G. Mathis – A niche CRO for ophthalmic studies and medical device investigations covering Europe
2009
Foundation of Clinical Investigations EOOD, Bulgaria
2013
Foundation of Appletree sprl, Belgium
(specialized in global Regulatory Affairs)
Merger of Clinical Investigations Group and Appletree AG to Appletree CI Group
– It’s a CRO offering full service for clinical trials inclusive regulatory affairs. Focusing on ophthalmology, dermatology, medical device investigations and pediatric studies
Foundation of Appletree CI, sp.z.o.o., Poland
2014
Integration of Brunner & Hess Data Management and Biostatistic – CSO offering all clinical trials services inhouse.
2017
Divestment
2019
Focus on Clinical & Consulting Services, offering full service together with preferred partners.